We have noticed a significant increase in the number of requests we are
receiving for 25OHD and are trying to establish whether it is always
necessary to measure 25OHD itself or if PTH can be used as a first line
test, with 25OHD being measured only if the PTH is raised. I've come
across a couple of papers which recommend the above approach but have also
read several which suggest that PTH is no substitute for 25OHD as it can be
normal in vitamin D deficiency and shows poor correlation with 25OHD, with
the relationship between the 2 analytes varying with age.
It would be useful to know the approach taken by other labs and I'd be
grateful for any references which decisions have been based on.
Thank you
Victoria Clough
Pre-Registration Clinical Biochemist
King George Hospital, Goodmayes
------ACB discussion List Information--------
This is an open discussion list for the academic and clinical
community working in clinical biochemistry.
Please note, archived messages are public and can be viewed
via the internet. Views expressed are those of the individual and
they are responsible for all message content.
ACB Web Site
http://www.acb.org.uk
List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html
List Instructions (How to leave etc.)
http://www.jiscmail.ac.uk/
|