The mass of salivary gland tissue is similar to that of the pancreas so their relative contributions to total serum amylase in health are about equal. The extent to which the amylase level increases in disease will depend on the severity of the tissue destruction/obstruction, and cannot per se indicate its origin. Simultaneous inflammation of both types of gland can occur.
Regards,
Jeff Davies
>>> "Dr. Michael Steiner" <[log in to unmask]> 27/11/2007 13:00:18 >>>
Dear Lab Community,
Textbooks state that amylase is increased in salivary gland disease
(mumps, duct obstruction etc.) and that this can be traced by additional
testing (lipase, pancreas amylase etc.).
However, what the textbooks do not state is the amount of total amylase
usually seen in salivary gland disease.
Is there experience you may wish to share ?
Better even, some rule of thumb (> xyz ULN is likely/unlikely (not)
salivary in origin?)
Thank you for your input.
Mike
Michael Steiner
Institute of Clinical Chemistry & Laboratory Medicine
University of Rostock
D-18057 Rostock
GERMANY
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