Could such solvent ordering be a byproduct of unusually low solvent
content as both of the structures seem to have (1h6w & 1ocy)? Perhaps
cryoprotectant did not penetrate the solvent channels, but the
crystal maintained its integrity nevertheless?
On Aug 28, 2007, at 1:14 AM, Kevin Cowtan wrote:
> Wow! Those are two pretty amazing structures.
>
> For those of you who haven't had a look, the ordered molecules are
> in layers with *huge* gaps in between, much greater than in 2hr0.
>
> And yet both of these structures were solved with experimental
> phasing (SIRAS) unlike 2hr0, and the data is to higher resolution.
>
> Mark J. van Raaij wrote:
>> With regards to our structures 1H6W (1.9A) and 1OCY (1.5A), rather
>> than faith, I think the structure is held together by a real
>> mechanism, which however I can't explain. Like in the structure
>> Axel Brunger mentioned, there is appreciable diffuse scatter,
>> which imo deserves to be analysed by someone expert in the matter
>> (to whom, or anyone else, I would gladly supply the images which I
>> should still have on a tape or CD in the cupboard...). For low-res
>> version of one image see http://web.usc.es/~vanraaij/diff45kd.png
>> and http://web.usc.es/~vanraaij/diff45kdzoom.png
>> two possibilities I have been thinking about:
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