Dear Colleagues,
I have received the following from Dr. Ahmad Tashfeen.
If anyone can help him I should be grateful if they would respond to
him directly.
All good wishes,
Olive
Olive Goddard
Centre and Editorial Manager
Centre for Evidence-Based Medicine
Department of Primary Health Care
Old Road Campus, Headington
Oxford, OX3 7LF
.....................................................................
Tel: +44 (0)1865 289337 email: [log in to unmask]
Fax: +44 (0)1865 289336 web: www.cebm.net
Mobile: 07804 625002 web: www.cebmh.com ( http://www.cebmh.com )
>>> "tashfeen.ahmad" <[log in to unmask]> 31/01/2007 15:21 >>>
Dear Dr. Goddard,
I am a researcher in Karachi, Pakistan. We are trying in our department
to gain knowledge of evidence base of research articles. I am also
interested in attending one of your workshops, if there is one nearby.
We are currently reviewing some research abstracts and trying to
"roughly" classify them according to the CEBM guidelines. I would like
your help in classifying the following three abstracts. I know that the
information in the abstracts may not be enough, but we have to take them
at their face value.
Thanking you
Sincerely,
Dr. Tashfeen Ahmad, FCPS, PhD
Senior Instructor Research
Departments of Surgery and BBS
Aga Khan University, Karachi, Pakistan
Tel. +92 (0) 21 486 4350
+92 (0) 21 486 4938
Fax. +92214932095
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J Coll Physicians Surg Pak. 2006 May;16(5):364-7.
A study of colorectal polyps.
Ahmad I, Khan AA, Alam A, Butt AK, Shafqat F, Sarwar S.
Department of Gastroenterology and Hepatology, Sheikh Zayed Hospital
(SZH), Lahore.
Objective: To determine various features of colorectal polyps and to
evaluate the safety of colonoscopic polypectomy. Design: Case series.
Place and Duration of Study: The Department of Gastroenterology and
Hepatology, Federal Postgraduate Medical Institute, Shaikh Zayed
Hospital, Lahore, from January 1987 to January 2004. Patients and
Methods: This study was based on data analysis of 393 patients who
underwent colonoscopic polypectomy at our institution during 17 years
from January 1987 to January 2004. Presenting complaints of patients
were noted. Polyps were evaluated in terms of size, site, number and
histopathology. Results: Among 393 patients, 268 were male and 125
female. Presenting complaints were bleeding per rectum in 339 patients,
diarrhea with blood in 34 and without blood in 6 patients, and lower
abdominal pain in 12 patients. Two patients were being investigated for
iron deficiency anemia. Two hundred and sixty-four patients had juvenile
polyps, 39 had adenomatous polyps, 39 hyperplastic polyps, 39
inflammatory polyps, 3 malignant polyps and 2 patients had familial
polyposis. Histopathological reports were not available in 7 patients.
Size of the polyps ranged from 0.3cm to 3.0 cm. Left colon was involved
in 353 patients, transverse colon in 15, right colon in 8 patients and
diffuse involvement of colon found in 17 patients. Bleeding following
polypectomy occurred in 2% of the patients. No other procedure related
complication occurred. Conclusion: Juvenile polyps were the commonest
variety of polyps in our study. Colonoscopic polypectomy has very low
complication rate.
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J Coll Physicians Surg Pak. 2006 Jun;16(6):416-9.
Mental distress in mothers of child psychiatric patients.
Syed EU, Zuberi SI.
Department of Psychiatry, The Aga Khan University, Karachi, Pakistan.
[log in to unmask]
OBJECTIVE: To determine whether caring for a child with mental health
issues could lead to mental distress among mothers. DESIGN:
Cross-sectional study. PLACE AND DURATION: Outpatient Clinics of The Aga
Khan University Hospital and PNS Shifa Hospital, Karachi, from January
to June 2005. PATIENTS AND METHODS: A total of 238 consecutive mothers
bringing their children to child psychiatric and pediatric clinics were
recruited over a 6-month period. As per inclusion criteria, 106 mothers
of child psychiatric patients were compared to 132 mothers taken from
pediatric clinics. They were asked to fill out a psychiatric screening
instrument (WHO SRQ-20). Mothers' mental distress (score>or=10 on
SRQ-20) and other potential risk or protective factors were measured.
RESULTS: Mental distress among mothers determined by WHO SRQ-20 was
associated with their child attending a psychiatric clinic (odds ratio
2.51, 95% confidence interval 1.38-4.51). This association remained
significant for age of mother being less than 30 years. No significant
association was found with the number of children and duration of
marriage. CONCLUSION: Mental distress among mothers is associated with
the child having psychiatric problems. These mothers may represent a
group who are at higher risk of depression. Early recognition and
treatment of mental health problems in mothers may help reduce
psychiatric morbidity in children.
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J Coll Physicians Surg Pak. 2006 Jul;16(7):445-9.
Intraerythrocyte and serum electrolytes in diabetic patients with
hypertension.
Yasmin F, Haleem DJ, Haleem MA.
Department of Biochemistry/Unit, Bio-Medical Engineering Department,
NED University of Engineering and Technology, Karachi.
OBJECTIVE: To determine the serum and intraerythrocyte concentrations
of vasoactive ions in patients of diabetes mellitus of either gender
with hypertension. DESIGN: Cross-sectional study. PLACE AND DURATION OF
STUDY: The Department of Biochemistry, University of Karachi, from
May-June 2002. PATIENTS AND METHODS: The study was conducted on 48
volunteers. Out of 48, 24(12 men and 12 women) were hypertensive
patients with diabetes mellitus. Remaining (12 men and 12 women) were
normal healthy subjects. Biochemical estimations were done by flame
photometry and spectrophotometry. Data were analyzed by Two-way ANOVA
followed by Newman-Keuls test. RESULTS: A decrease in serum
concentrations of sodium, calcium, magnesium, phosphorus, chloride and
intraerythrocyte potassium and an increase in the levels of glucose,
haematocrit and intraerythrocyte sodium was observed in both male and
female patients with diabetes mellitus and hypertension. No significant
changes were observed in serum potassium levels. CONCLUSION: The results
suggest that dysregulations of electrolyte balance caused by
hyperinsulinemia or altered glucose metabolism may lead to
hypertension.
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