Just looked at the latest NEQAS report (under a pile of papers on my desk), and if the kit is the Applied Biotech Surestep hCG Combo, then there is definatley a problem with the kit. Quoted detection limit 20.
Sample X193 (50 u/L hCG added) 5 positive and 6 negative
Sample X194 (Pregnancy Urine value around 7000) 8 positive and 3 negative.
I'd steer clear of this one, and possibly report them, brings back memories another kit in the last couple of years.
Gary
G. C. Mascall
Consultant in Clinical Biochemistry
Worcestershire Acute Hospitals NHS Trust.
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Tel: 01562 823424 extn 53464/53136
-----Original Message-----
From: Clinical biochemistry discussion list
[mailto:[log in to unmask]]On Behalf Of Joan Pearson
Sent: 08 July 2005 15:35
To: [log in to unmask]
Subject: 'Surestrip' Pregnancy test
One of our A&E consultants has enquired about possible reasons for two false negatives on this kit.
Both were done in the early hours of the morning, one on a patient 1/52 after missed period and the other in a patient who was around 8 weeks pregnant. The kit insert states that urine taken at any time is OK, but obviously an early morning specimen is preferred and a very dilute urine might be a problem particularly in very early pregnancy. It claims to detect hCG concentrations of 20 mIU/ml or more.
In the absence of any further information (interfering substances crossed my mind) I suggested training/competency - possibly someone who was not familiar with the procedure doing it during the night under pressure.
Any other suggestions?
Thanks
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------ACB discussion List Information--------
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