Dear all
I have a patient who developed an asymptomatic increase in his CK to
~2000u/L while taking fenofibrate monotherapy for his mixed hyperlipidaemia.
There were no obvious alternative causes for the raised CK and it has since
come down to 170u/L on stopping.
My question is, in patients in whom lipid lowering treatment is highly
justified but who have proven muscle toxicity to a statin or fibrate, what
do readers of the mailbase do? My gut feeling is to try pravastatin or
fluvastatin when it comes to statins, but I can find no evidence for the
safety, or otherwise, in restarting these individuals on other agents.
Eric
Dr. Eric S. Kilpatrick
Consultant in Chemical Pathology
Department of Clinical Biochemistry
Hull Royal Infirmary
Anlaby Road
Hull HU3 2JZ
Tel 01482-607708
Fax 01482-607752
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