Hello Tanya.
I would interpret this question as being about Harm/Aetiology in the first
instance.
For that reason, I would look first for an RCT which compared patients on
exelon with those on antivert as well. Next would be observational studies
(cohort or case-control).
cheers
Douglas
on 27/4/04 6:53 PM, Feddern, Tanya at [log in to unmask] wrote:
> Hello. A student wrote this PICO: "In an 80 year-old Hispanic female with
> Alzheimers taking Exelon, will Antivert in the treatment of vertigo produce
> increased Alzheimer symptoms?"
>
> The student wants to know about the possibility of harm occurring *if* the
> patient takes the second drug. In other words, the student wishes to fortell
> the future about iatrogenic effects. In cases where the patient hasn't
> experienced harm nor has been exposed to the noxious exposure, is the
> Prognosis filter category best? Or, would it be better for the student to try
> the Etiology/Harm filter category first and then use the Prognosis fiter if
> s/he didn't find relevant studies? BTW, here's the list of terms we use in
> our filters: http://calder.med.miami.edu/medline_manual.html#33
>
> Please let us know what you think. We appreciate your comments and will
> summarize the answers to the list.
>
> Thank you,
>
> Tanya (and John)
> Tanya Feddern, MLIS, AHIP, MOT, OTR/L
> John D Jones, Jr, MSIS
> http://www.geocities.com/nqiya/EBMbib.html
> http://www.geocities.com/nqiya/index.html
> Evidence-Based Medicine Assistant Professors; Reference & Education Services
> Librarians
> University of Miami School of Medicine, Louis Calder Memorial Library
>
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