>
>Dear Mail list
>This is not a question about statistics and EBM
>It is only to see if anyone in the list has come across any evidence based
>objection to the use of intravenous (IV) VZIG
>
>The Nelson Text Book of Pediatrics 17th Edition suggests intramuscular
>(IM) use
>The Manual of Neonatal Care by John Cloherty and Ann R Stark say VZIG must
>be used Intramuscularly ONLY
>
>A intravenous preparation is in the market. (Varitect CP Biotest Pharma
>Dreieich Germany)
>
>Were the text books written before the IV preparation was available and is
>that why the IM route is recommended?
>Does anyone know of any evidence against IV preparations or have
>experience with its use?
>
>I write because we recently had the mortification of seeing twins die with
>pulmonary hemorrhage 5 minutes of one another within 15 minutes of being
>given the IV preparation (given slowly over 4 hours.)
>Their mother had chicken pox 5 days prior to delivery.
>There was no other antecedent cause for both babies to die so precipitously.
>
>It is then we realized there was no text book support for the use of IV VZIG
>
>We will be thankful for any leads
>
>Sincerely
>
>Jacob M. Puliyel MD MRCP M Phil
>Head of Pediatrics
>St Stephens Hospital
>is Hazari
>Delhi 110054
>India
>
>
>
>______________________________
>
>Residence eMail: [log in to unmask]
>Residence Phone: 00-91-11-3946388
>eFax UK 07092-124285
>Fax 00-91-11-23932412
>
>
>Work Phone: 00-91-11-3966021 to 27
______________________________
|