Microalbumin testing by immunoturbimetric techniques is very labour
intensive and not that pleasant! due to the pre-analytical steps required,
i.e. centrifugation and transfer to a tube suitable for the analyser, and
the inherent unpleasant smell of urine. Couple this with doing up to three
samples on each patient, and given the numbers of diabetics. We are
expecting about 100 samples a day to be processed. Given that the majority
of samples will be negative, It would therefore seem preferable to try and
minimise the impact on laboratories by looking at POCT in the surgeries to
rule out negatives and only send samples which have been found to be
positive by POCT to the Laboratory for further testing. Admittedly this
would require resourcing as well, but keeps the majority of samples out of
the Lab. I agree with Catherine that the Micral 11 strips are not ideal, and
are technically quite demanding for the average practice nurse. The Bayer
Microalbumin strips are not technically demanding and also semi quantitate
creatinine, and can be instrument read, so are worth investigating. Has
anyone done a thorough evaluation of these strips?
[log in to unmask]
-----Original Message-----
From: Fry, John [mailto:[log in to unmask]]
Sent: 26 February 2004 16:23
To: [log in to unmask]
Subject: Microalbumin screening - pre analytiical
Do many laboratories or possibly GP surgeries screen for microalbumin using
either dip sticks or any other system to reduce the massive increase that
many are experiencing with microalbumin requests.
If pre-analytical screening is undertaken, what kits are used?
If laboratory analysis is then carried out, how are results reported - are
both the urine creatinine, microalbumin and then the microalbumin/creatinine
ratio reported on the results or merely the ratio?
John Fry
Worthing
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