the following references may be of interest:
best
bd
27. Sandercock P, Roberts I: Systematic reviews of animal experiments. Lancet 2003; 360: 586.
34. Horn J, Limburg M: Calcium antagonists for acute ischemic stroke. In: The Cochrane Library: Oxford: Update Software 2002; Issue 2.
35. Horn J, R.J. dH, Vermeulen M, Luiten PGM, Limburg M: Nimodipine in animal experiments of focal cerebral ischemia: a systematic review. Stroke 2001; 32: 243-38.
Benjamin Djulbegovic, MD,PhD
Professor of Oncology and Medicine
H. Lee Moffitt Cancer Center & Research Institute
at the University of South Florida
Department of Interdisciplinary Oncology
12902 Magnolia Drive
Tampa, FL 33612
Editor: Cancer Treatment Reviews (Evidence-based Oncology Section)
http://www.harcourt-international.com/journals/ctrv/
e-mail:[log in to unmask]
http://www.hsc.usf.edu/~bdjulbeg/
phone:(813)979-7202
fax:(813)979-3071
-----Original Message-----
From: Janet Martin [mailto:[log in to unmask]]
Sent: Monday, July 14, 2003 3:06 PM
To: [log in to unmask]
Subject: Re: systematic review of basic laboratory research
Luciano,
I would be surprised if you found exactly what you are looking for!
If you are intested in creating your own guidelines, you may
find the NOS scale (developed by a collaboration
between Ottawa and Australia) helpful for providing some guidance.
Best regards,
Dr. Janet E. Martin, PharmD
Coordinator, Drug Use Management
Project Lead, Evidence-Based Prescribing Initiative
Manager, Ontario Regional Adverse Reaction Reporting Centre
Lecturer, Department of Physiology & Pharmacology, University of
Western Ontario
Associate Scientist, Lawson Health Research Institute
London Health Sciences Centre
Room 1PH12, 339 Windermere Road
London, Ontario
Canada N6A 5A5
tel: 519-685-8500 x35882
fax: 519-663-2968
email: [log in to unmask]
>>> L Mignini <[log in to unmask]> 07/14/03 02:33PM >>>
Dear Members
I am a WHO research training fellow in systematic reviews. I would like
to develop methods of systematic review of basic scientific experiments
examining biological plausibility of causation or aetiology. My topic
will be 'hyperhomocysteniemia as a cuasal factor for oxidative stress
and preeclampsia'.
To my knowledge this type of evidence is seldom reviewed in a
systematic way and its quality is not assessed in a robust manner. I
have so far unearthed only one example of such a systematic reviews (our
searches continue). There is virtually no published literature on
quality assessment or good research guidelines for laboratory
researchers about methodological things.
i am writing to you in the hope that you will have some knowledge of
reviews and methodological guidelines in this field. this will help me
develop means to systematically review basic science literature. thanks
Luciano Mignini
Reseach Fellow OB/GYN
Brimingham Women's Hospital NHS Trust
Metchley Park Lane
Edgbaston
Birmingham
B15 2TG
[log in to unmask]
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