Hi, yep this should be possible, hopefully. What you are asking is: can
you take SIENA results and do local stats on the edge movement in standard
space?
We submitted an abstract to ISMRM this year doing this - it's early days,
but easy to try...
draft abstract at
http://www.fmrib.ox.ac.uk/~steve/ftp/ismrm2003_nds.doc
Thanks, Steve.
On Wed, 15 Jan 2003, Erik-Jan Vlieger wrote:
> Hi,
>
> I have a group of 19 patients, in whom we are looking for a treatment effect,
> and we expect that the volume of the hippocampus has increased as a result of
> the treatment. From these 19 patients there is both a pre- and post-treatment
> 3D T1 weighted scan.
>
> I thought I would use SIENA to find pre-post treatment changes, but after that
> I would like to register the effects somehow to talairach space, and see if
> there is a significant group effect.
>
> Is this at all possible?
>
> Thanks,
> --
> Erik-Jan Vlieger
> Academic Medical Center
> Dept. of Radiology, G1-209
> P.O. Box 22660
> 1100 DD Amsterdam
> The Netherlands
> email: [log in to unmask]
> Phone: +31 20 5664975
> Fax: +31 20 5669753
>
Stephen M. Smith
Head of Image Analysis, FMRIB
Oxford University Centre for Functional MRI of the Brain
John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK
+44 (0) 1865 222726 (fax 222717)
[log in to unmask] http://www.fmrib.ox.ac.uk/~steve
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