Following the supervision of a successful IBMS project to perfect (?) a RBC
transketolase assay, I did some costings and worked out that the total cost
of performing the assay would fund 60 years of thiamine treatment at current
prices. I have never requestd one since!
with best wishes
Richard
Richard Mainwaring-Burton
Consultant Biochemist
Queen Mary's Hospital
Sidcup, Kent
DA14 6LT
020-8308-3084
-----Original Message-----
From: Roberta Goodall
[mailto:[log in to unmask]]
Sent: 11 August 2003 14:21
To: [log in to unmask]
Subject: Red Cell Transketolase
The laboratory to which we send our (rare) requests for red cell
transketolase (an assay that required us to send a whole blood sample) has
decided to withdraw the assay from its repertoire. A check on assay finder
revealed 3 labs, all of which require washed red cells (+ haemotocrit
measured in a capillary). Preparing cells is rather more than we wish to do.
I have two questions for list members.
Is there any longer any real clinical value in this assay (or can we
recommend just giving thiamine) ?
If there are good reasons for measuring the enzyme, are there any labs out
there that do it and will accept a whole blood sample; or is this not a good
practice for this assay anyway?
Roberta Goodall
Clinical Biochemistry
North Bristol Trust
------ACB discussion List Information--------
This is an open discussion list for the academic and clinical
community working in clinical biochemistry.
Please note, archived messages are public and can be viewed
via the internet. Views expressed are those of the individual and
they are responsible for all message content.
ACB Web Site
http://www.acb.org.uk
List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html
List Instructions (How to leave etc.)
http://www.jiscmail.ac.uk/
------ACB discussion List Information--------
This is an open discussion list for the academic and clinical
community working in clinical biochemistry.
Please note, archived messages are public and can be viewed
via the internet. Views expressed are those of the individual and
they are responsible for all message content.
ACB Web Site
http://www.acb.org.uk
List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html
List Instructions (How to leave etc.)
http://www.jiscmail.ac.uk/
|