The treatment level depends on whether they have symptoms: I have a patient
with proven gout [they've removed urate Xtals from his joints], but whose
basal urate has not exceeded 440. I have others who have no problem
whatsoever with urates of 600+.
So the answer is treat the symptoms - not the number
TIM
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*********
Prof. Tim Reynolds,
Clinical Chemistry Department,
Queens Hospital,
Belvedere Rd.,
Burton-on-Trent,
STAFFORDSHIRE,
DE13 0RB,
UK.
tel: 01283 511511 ext. 4035
fax: 01283 593064
email: [log in to unmask]
alternative email for the all too frequent occasions when the NHS email
connection doesn't work:
[log in to unmask]
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> -----Original Message-----
> From: [log in to unmask] [mailto:[log in to unmask]]
> Sent: 30 May 2003 10:56
> To: [log in to unmask]
> Subject: What urate level should be treated?
>
>
> A GP has a female patient with hypertension and on a thiazide
> diuretic with
> a urate of 456 umol/L (we quote a ref range of 155-357). The
> level does not
> appear to be increasing with time. She would prefer not to change the
> diuretic, and wonders at what level one should treat hyperuricemia, or
> change diuretic. She also has a male of similar level- our
> ref range 208-428
> umol/L, referred from a well screening programme, and he is
> well. Is there
> an acceptable grey area, in which the urate is "abnormal",
> but not requiring
> treatment, just monitoring.
> Thanks
>
> ____________________________________________________________
>
> Dr. Helen Grimes, Dept. of Clinical Biochemistry, UCH, Galway, Ireland
>
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