>
> Robin Marks said:
> >
> > In summary 'HbA1c measurement cannot be used for the diagnosis of
diabetes
> > because of analytical or standardisation problems in the assay'.
> >
> > Do we agree ?
> >
> Yes, but more due to the inherent problems with HbA1c itself, which will
> still be present even once all analytical and standardisation issues have
> been addressed.
>
> For example, in the DCCT study it has been shown that patients with a mean
> lab plasma glucose of 10mmol/L can have a HbA1c anywhere between 6 and
11%!
> (Rohlfing CL, Wiedmeyer HM, Little RR, et al. Diabetes Care 2002
> ;25:275-8).
>
> Eric
> Dr. Eric S. Kilpatrick
> Consultant in Chemical Pathology
> Hull Royal Infirmary
> Anlaby Rd
> Hull HU3 2JZ
> Tel: 01482-607708
> Fax: 01482-607752
>
------ACB discussion List Information--------
This is an open discussion list for the academic and clinical
community working in clinical biochemistry.
Please note, archived messages are public and can be viewed
via the internet. Views expressed are those of the individual and
they are responsible for all message content.
ACB Web Site
http://www.acb.org.uk
List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html
List Instructions (How to leave etc.)
http://www.jiscmail.ac.uk/
|