Dear Aubrey,
I would have thought a fresh "clean" sample put through a full urine amino
screen ought to be helpful, given that cystinuria affects epithelial
function generally including the gut.
Otherwise serum/plasma analyses, including PTH and maybe oxalate as well as
the more usual analytes, would probably cover what you need.
But one of the alternative approaches to GFR will presumably be indicated
instead of creatinine clearance.
Best wishes,
Les
> From: ablumsohn <[log in to unmask]>
> Reply-To: ablumsohn <[log in to unmask]>
> Date: Mon, 13 Oct 2003 18:04:16 +0100
> To: [log in to unmask]
> Subject: Urinary analytes related to stones after ureteric diversion
>
> Potentially difficult problem - patient with massive
> longstanding nephrolithiasis (onset age 25 or so),
> required unilateral nephrectomy, removal of bladder and
> implantation of ureters into a ileal conduit.
>
> No relevant investigations were carried out w.r.t cause
> of the nephrolitiasis prior to surgery. Clearly we need
> to do all we can to sustain her remaining kidney.
>
> Any idea whether "urinary" cysteine, oxalate and other
> pertinent aspects of a stone screen might be
> interpretable after passing through a bit of bowel?
>
> Aubrey
>
> --
> ||===========================================
> || Dr Aubrey Blumsohn
> || Senior Lecturer in Metabolic Bone Disease
> || Division of Clinical Sciences (NGHT)
> || Clinical Sciences Centre
> || Northern General Hospital, Herries Road
> || Sheffield S5 7AU, England
> || phone: 114-2715963(office),114 2714705(sec)
> || fax: 0114 261 8775 (fax)
> ||===========================================
>
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