As far as I am aware there is no necessity to treat FH patients
during pregnancy, as their cardiovascular risk will not be substantially
increased for a relatively short period of time compared to a life-time of
exposure to a high LDL cholesterol. Triglycerides are however a different
"kettle of fish" as there is a substantial risk of pregnancy induced
pancreatitis which can be life-threatening for both mother and unborn child
Simon Fleming
Royal Cornwall Hospital
-----Original Message-----
From: David Williams [mailto:[log in to unmask]]
Sent: Friday, October 03, 2003 20:57
To: [log in to unmask]
Subject: Re: STATINS AND THIRD TRIMESTER OF PREGNANCY
We have recently diagnosed gross hyperlipidaemia in a lady approaching
delivery (total cholesterol 15.6 mmol/L and triglycerides 51.8 mmol/L).
There were no other predisposing causes (e.g. diabetes, alcoholism
hypothyroidism, etc).
After delivery (approx 3/52 afterwards) her lipids were again tested - they
were then virtually normal (chol 5.0 and TGs 2.0). There is apparently a
familial condition, hyperlipidaemia of pregnancy, which corrects itself
after delivery.
We may be doing further tests on this patient - I may pass these on if they
are of any interest.
David L. Williams
-----Original Message-----
From: Clinical biochemistry discussion list
[mailto:[log in to unmask]]On Behalf Of
[log in to unmask]
Sent: 03 October 2003 17:56
To: [log in to unmask]
Subject: STATINS AND THIRD TRIMESTER OF PREGNANCY
Does anyone have experience / data on use of statins in third trimester of
pregnancy? I realise that they are contraindicated in preg but was
wondering whether this was related to 1st trimester effects? Am trying
Questran in this patient at the moment.
Many thanks
Rob
Dr Robert Lord
Department of Clinical Biochemistry
Rotherham District General Hospital
Moorgate Road
Oakwood
Rotherham
S60 2UD
Tel 01709 820000
E mail [log in to unmask]
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