Which method do you use for measuring HDL?
We have seen such results with the Roche method (2nd generation) used with a
modular analyzer in patients with monoclonal proteins and in patients with
high levels of polyclonal gammaglobulins. (case report accepted by Ann Clin
Biochem)
So I would suggest to do a SPE on this patients serum.
Andries
Dr. A. J. Bakker, Klinisch chemicus,
St. Klinisch Chemisch Laboratorium,
Postbus 850,
8901 BR LEEUWARDEN.
Tel.: 058-2888444
Fax: 058-2882227
E-mail: [log in to unmask]
> -----Oorspronkelijk bericht-----
> Van: Mohmed Ashmaig [SMTP:[log in to unmask]]
> Verzonden: vrijdag 15 augustus 2003 3:06
> Aan: [log in to unmask]
> Onderwerp: undetected HDL and low cholesterol
>
> Dear All,
>
> Thanks to every one reply to my last e-mail address
> (corrected Calcium).
>
> I have interested case, 82 years old man admitted last
> January 2003 for Rash in groin and cellulitis. the
> only abnormal chemistry was Alp of 187 (ref. 31-129
> u/l).
>
> His Cholesterol 135 (range 120-225 mg/dl), Tirg 125
> (range 35-160 mg/dl), HDL 32 (range 23-150 mg/dl), LDL
> 78 (range 0-185 mg/dl).
>
> He admitted again on August 13, 2003 for same medical
> reason plus liver abnormalities.
>
> His lipids today; chol 53 mg/dl, Trig 86 mg/dl, HDL
> <0.1 mg/dl, LDL waiting for result from Reference
> laboratory, I will e-mail it as soon as received.
>
> He is not on lipid lowering medicine.
>
> His list of medications are; levofloxacin,
> spironolactone, Trandolapril, Kcl, Aspirin,
> Phytonadone, pantoprazole sodium, Metoprolol,
> Nitroglycerin subl, hydrocodone.
>
> all lipids were repeated with new sample for
> confirmation.
>
> any idea why his HDL is undetectable and his chol so
> low ???
>
> may be due to liver disease????
>
>
> Thanks to all
>
>
> Mohmed Ashmaig
> Barton Memorial Hospital
> USA
>
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