Dear Mohammad
As a follow -up to your posting on how to intrepret fasting plasma glucoses
> 7.0 mmol/L in the absence of glucose > 11.1 mmol/L the DECODE Study
(Lancet 354, 617 1999) looked at 17,300 GTT's on men. Approx 25% had some
form of glucose intolerance by WHO criteria and of these some 4% had FPG >=
7.0 mmol/L but 2hr glucose < 7.8 mmol/L and another 5% had
FPG >= 7.0 mmol/L with 2 hr glucoses between 7.8 and 11.1 mmol/L.
Should these men be labelled as diabetic? It would seem so. The hazard
ratios for death within a median period of follow up of 7.3 years was 1.8
for both groups when compared with a control population with normal glucose
tolerance. (The figures for women were essentially similar).
Dave Hullin
Dr D A Hullin
Department of Clinical Biochemistry
Royal Glamorgan Hospital
Ynysmaerdy
Llantrisant
CF72 8XR
Tel: 01443 443358
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