Date sent: Thu, 24 Jul 2003 16:39:53 +0100
Send reply to: Mohammad Al-Jubouri <[log in to unmask]>
From: Mohammad Al-Jubouri <[log in to unmask]>
Subject: Re: Creatine Phosphate and High Levels of CK
To: [log in to unmask]
Mohammad,
In statin (and Fibrate) induced myositis, i.e. CK > 10 time URL, the
CK frequently goes back to the pre-treatment level within 48 hours.
Not sure about other drugs.
Did the patient continue to exercise or not?
Pat
> Raised CK is more likely to be due physical activity
> because of rapid decline over three days. Drug induced
> rise in CK is unlikely to settle over this short
> period.
>
> Mohammad
> --- LLOYD Geoff
> <[log in to unmask]> wrote: > A
> 26 year old who has been on Olazipine (atypical
> > neuroleptics) for
> > schizophrenia was referred to us because of high
> > CK:890. In addition to
> > Olazipine, the patient has also been taking creatine
> > phosphate for body
> > building purposes. The creatine phosphate was not
> > prescribed by any
> > practitioner. In order to find the possible cause of
> > the raised CK, both
> > medications were stopped, and 3 days later, the CK
> > levels were back to
> > normal (117)! The pertinent question is:
> > Does anyone have any experience with high CK
> > following prolonged
> > administration of creatine phosphate or, could this
> > be due to olazipine
> >
> > Many thanks
> >
> > Dr Rasaq Olufadi
> >
> > Please reply to:
> > [log in to unmask]
> >
> >
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> =====
> Dr. M A Al-Jubouri
> Consultant Chemical Pathologist
>
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