We have observed several patients with decreased CK activity - below
detectable limits. Thus far, these have always been elderly patients
with low muscle mass.
James D. Peele, Ph.D.
Director of Clinical Chemistry
Baptist Medical Center
800 Prudential Drive
Jacksonville, FL 32207
Voice 904-202-2675
Fax 904-202-2795
E-mail [log in to unmask]
>>> Cutler Margaret <[log in to unmask]> 01/16/03
06:33AM >>>
Any suggestions on the cause of an undetectable CK activity?
The patient is a 76yr old Caucasian male, with a history of renal
failure and fast AF. Current creatinine around 180.
On looking back, he had a CK of 76 IU/L in 1997 and in 1999 had an MI
when his CK rose to 407 IU/L. However there was a query about
reinfarction 1 week later and at that time his CK was 15 IU/L. On his
most recent admission, CK was undetectable on our Olympus 640 - this was
confirmed on a Vitros analyser. Current drug therapy - digoxin,
prednisolone, aspirin, ranitidine, amiodarone, amoxycillin (chest
infection), frusemide and heparin. Patient is thin & wasted - but
should that alone leave him with an undetectable CK?
Margaret F Cutler
Department of Clinical Chemistry
Dewsbury and District Hospital
Halifax Rd
Dewsbury
WF13 4HS
West Yorkshire
Tel. +(0)1924 816236
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