Dear Martin
No cutoff - its a continuum. Is cleared (mainly) by glomerular
filtration (probably), and goes up in proportion to creatinine
(roughly). When/whether it becomes uninterpretable depends on what you are
trying to do.
Aubrey
Bone Metabolism Group
University of Sheffield
HMC> Has anyone any information on the effect of renal insufficiency on serum
HMC> ß-CTx (ß-Crosslaps) concentration? Is there a creatinine clearance cut-off
HMC> where the test becomes uninterpretable? It is difficult to get hard data on
HMC> this.
HMC> Thanks
HMC> Martin Healy PhD
HMC> Principal Biochemist
HMC> St. James's Hospital
HMC> Dublin
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