before you do that, you should perhaps have a look at the very interesting
rapid responses which have been made to this article (bmj.com)
Joseph Watine, Hôpital de Rodez, France
>From: [log in to unmask]
>Reply-To: [log in to unmask]
>To: [log in to unmask]
>Subject: STATINS AT NIGHT
>Date: Tue, 14 Oct 2003 11:52:30 +0100
>
>In BMJ 4 Oct 2003 p788 the authors looked at simvastatin and showed that
>the cholesterol was higher if the drug was taken in the morning. Looking at
>the data reminded me of some calculations I had done a few years back for
>my MRCPath looking at what a clinically significant change in cholesterol
>was (rather than a statistically significant change). Used CVs for
>analytical and biological variation I think! Anyone else looked at this
>article and calculated out what you would expect a clinically significant
>change to be?
>
>Thanks
>
>Rob
>Dr Robert Lord
>Department of Clinical Biochemistry
>Rotherham District General Hospital
>Moorgate Road
>Oakwood
>Rotherham
>S60 2UD
>
>Tel 01709 820000
>E mail [log in to unmask]
_________________________________________________________________
Trouvez l'âme soeur sur MSN Rencontres http://g.msn.fr/FR1000/9551
------ACB discussion List Information--------
This is an open discussion list for the academic and clinical
community working in clinical biochemistry.
Please note, archived messages are public and can be viewed
via the internet. Views expressed are those of the individual and
they are responsible for all message content.
ACB Web Site
http://www.acb.org.uk
List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html
List Instructions (How to leave etc.)
http://www.jiscmail.ac.uk/
|