Dear Raj,
You posted:
"Recently there were concerns raised in our area about the effectiveness of
flu vaccination, particularly in health care staff and we are planning to
evaluate its effectiveness in coming few months. So, any references,
suggestions, advices, especially on selection of outcomes and use of any
frame works on this topic will be greatly appreciated".
It is not very clear from the above whether HCWs have raised concern on the
flu vaccination in general or vaccinating health care workers. Hope you find
the following information of some interest. Good luck in your evaluation.
Wilde JA, McMillan JA, Serwint J, Butta J, O'Riordan MA, Steinhoff MC.
Effectiveness of influenza vaccine in health care professionals: a
randomized trial. JAMA 1999 Mar 10;281(10):908-13
Saxen H, Virtanen M. Randomized, placebo-controlled double blind study on
the efficacy of influenza immunization on absenteeism of health care
workers. Pediatr Infect Dis J 1999 Sep;18(9):779-83
Govaert TM, Thijs CT, Masurel N, Sprenger MJ, Dinant GJ, Knottnerus JA. The
efficacy of influenza vaccination in elderly individuals. A randomized
double-blind placebo-controlled trial. JAMA 1994 Dec 7;272(21):1661-5
Govaert TM, Dinant GJ, Aretz K, Masurel N, Sprenger MJ, Knottnerus JA.
Adverse reactions to influenza vaccine in elderly people: randomised double
blind placebo controlled trial. BMJ 1993 Oct 16;307(6910):988-90
Margolis KL, Nichol KL, Poland GA, Pluhar RE. Frequency of adverse reactions
to influenza vaccine in the elderly. A randomized, placebo-controlled trial.
JAMA 1990 Sep 5;264(9):1139-41
Allsup SJ, Gosney M, Regan M, Haycox A, Fear S, Johnstone FC. Side effects
of influenza vaccination in healthy older people: a randomised single-blind
placebo-controlled trial. Gerontology 2001 Nov-Dec;47(6):311-4
Harrison J, Abbott P. Vaccination against influenza: UK health care workers
not on-message. Occup Med (Lond) 2002 Aug;52(5):277-9
Dey P, Halder S, Collins S, Benons L, Woodman C. Promoting uptake of
influenza vaccination among health care workers: a randomized controlled
trial. J Public Health Med 2001 Dec;23(4):346-8
Takahashi H, Tanaka Y, Ohyama T, Sunagawa T, Nakashima K, Schmid GP, Okabe
N. Evaluation of a mass influenza vaccination campaign. Jpn J Infect Dis
2001 Oct;54(5):184-8
Dille JH. A worksite influenza immunization program. Impact on lost work
days, health care utilization, and health care spending. AAOHN J 1999
Jul;47(7):301-9
Some information from CRD, York
http://nhscrd.york.ac.uk/online/dare/952722.htm
http://nhscrd.york.ac.uk/online/hta/998343.htm
Cheers & regards,
Badri
Dr.P.Badrinath M.D,M.Phil,(Epid)PhD(Cantab)DFPHM,MPH(Distinc)
Specialist Registrar in PHM & Honorary Clinical Lecturer,
Suffolk Public Health Network & University of Cambridge,
PO Box 170, St.Clement's Hospital,
Ipswich IP1 4LA, UK.
http://myprofile.cos.com/badrishanthi
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