But why would you want them! The only Clinical value of protein
electrophoresis and densitometry is to distinguish polyclonal increases
in immunolgobulins from monoconal and for paraprotein quantification
(reference value = 0), where immunochemical estimation can be
unreliable.
Anything else shown by EP is better quantified by specific protein
measurements. Low albumin - measure albuimn; low alpha-1 - measure
alpha-1 antitrypsin (if clincially indicated); raised alpha-1 & alpha-2
indicates acute phase response - quantifiy CRP; low immunoglobulins
assessed by quantification, low alpha-2 proteins of clinical relevance
are haptoglobin and caeruloplasmin - both need specific quantification.
Pam Riches
----- Original Message -----
From: PETER HOWELL <[log in to unmask]>
Date: Friday, July 26, 2002 10:48 am
> Would anyone be willing to share their reference ranges for serum
> proteinsfractions as per scanning densitometry of protein
> electrophoresis ?
>
> Thanx
>
> Peter
>
>
> Peter Howell
> Head Biomedical Scientist
> Medical Biochemistry Department
> Wrexham Maelor Hospital
> Wrexham
>
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