Dear Lance
The BNF (in the UK) provide Coronary Risk Predication Charts produced by the
Joint British Societies. These tables are use to classify patients into
various CHD risks. So there is no actual total: HDL cholesterol cut-off
value. We have started reporting this ratio on our reports, and they are
very much liked by the GPs.
Avril Owen
Principal Biochemist
Ysbyty Gwynedd
Bangor
Wales
-----Original Message-----
From: Lance Sandle [mailto:[log in to unmask]]
Sent: 31 January 2002 13:57
To: [log in to unmask]
Subject: Total to HDL cholesterol ratio
Dear Colleagues
Total:HDL ratio appears on various risk prediction
charts and in the literature. Though not at present
under pressure to provide this derived parameter on
lab reports, I would have to be confident that it has
been validated before doing so. Obviously I'm happy to
report total and HDL cholesterol, leaving those still
capable of long division to work out the ratio for
themselves. What I'm not happy to do is take
responsibility for a derived result of dubious
scientific provenance.
I've seen cut-off values of 4.0 and 4.5 quoted -
sometimes by the same author, hence my scepticism!
Has anyone got hard evidence of its validity?
=====
Dr Lance N Sandle
Consultant Chemical Pathologist
Department of Chemical Pathology
Trafford General Hospital, Moorside Road, Davyhulme
Manchester M41 5SL United Kingdom
Tel: +44(0)161 746 2473 Fax: +44(0)161 746 8545
e-mail: [log in to unmask]
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