Dear Colleagues
Total:HDL ratio appears on various risk prediction
charts and in the literature. Though not at present
under pressure to provide this derived parameter on
lab reports, I would have to be confident that it has
been validated before doing so. Obviously I'm happy to
report total and HDL cholesterol, leaving those still
capable of long division to work out the ratio for
themselves. What I'm not happy to do is take
responsibility for a derived result of dubious
scientific provenance.
I've seen cut-off values of 4.0 and 4.5 quoted -
sometimes by the same author, hence my scepticism!
Has anyone got hard evidence of its validity?
=====
Dr Lance N Sandle
Consultant Chemical Pathologist
Department of Chemical Pathology
Trafford General Hospital, Moorside Road, Davyhulme
Manchester M41 5SL United Kingdom
Tel: +44(0)161 746 2473 Fax: +44(0)161 746 8545
e-mail: [log in to unmask]
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