Elliott Simpson said..

> Well I said to check he'd not developed any silly dietary habit (e.g. a
high
> egg intake).

There is little relationship between dietary cholesterol (for example, from
eggs) and blood cholesterol. However, there is a strong relationship between
dietary fat (especially saturated) and serum lipids.

See:
Normal plasma cholesterol in an 88-year-old man who eats 25 eggs a day.
Mechanisms of adaptation. Kern F. N Engl J Med 1991; 324:896-899, Mar 28,
1991

for an extreme example. The paper did not mention if the chap lived alone!

Eric
Dr. Eric S. Kilpatrick
Consultant in Chemical Pathology
Hull Royal Infirmary
Anlaby Rd
Hull HU3 2JZ
Tel: 01482-607708
Fax: 01482-607725
----- Original Message -----
From: Simpson Elliott (MK) Top Grade Biochemist, Laboratory Directorate
<[log in to unmask]>
To: <[log in to unmask]>
Sent: Thursday, January 31, 2002 10:06 AM
Subject: FW: advice/ NEQAS Case 111


> Well I said to check he'd not developed any silly dietary habit (e.g. a
high
> egg intake).  If he isn't, leave him alone.  I believe that you not only
> need to reduce someone's cholesterol, but that you have to maintain it at
> the lower level for three years before any statistical benefit is
obtained.
> So I said that an 80 year old can have any cholesterol level he likes,
after
> all it was Christmas.
>
> It will not surprise readers to know (a) that I got a negative mark and
(b)
> I'll not be staying in the scheme after they start charging for it!
>
> Elliott Simpson
>
> -----Original Message-----
> From: Dr Howard Worth, Clinical Chemistry @KMC
> [mailto:[log in to unmask]]
> Sent: 31 January 2002 08:27
> To: [log in to unmask]
> Subject: Re: advice/ NEQAS Case 111
>
>
> Following Chris Lovell Smith's comments, I wonder about the efficacy of a
> major investigation (and treatment) of an 80 your old with no previous
> history of lipidemia.   This point of view did not attract the sympathy of

> the assessors!
>
> Howard Worth
>
> > -----Original Message-----
> > From: Chris Lovell-Smith [SMTP:[log in to unmask]]
> > Sent: 31 January 2002 01:43
> > To:   [log in to unmask]
> > Subject:      FW:      advice/ NEQAS Case 111
> >
> > Hi, I also wonder about the [highly scoring] suggestion that an
> > 80-year-old man might be presenting with FH, presumably for the first
> > time? I thought it very unlikely, and would be pleased to get some
> > references to clarify my thinking. Thanks
> > Dr Chris Lovell-Smith
> > Chemical Pathologist and Clinical Leader
> > Healthlab Otago, Dunedin Hospital
> > DUNEDIN, NZ
> > 64 3 474 7925
> >
> >
> > -----Original Message-----
> > From: Patel Bharat [mailto:[log in to unmask]]
> > Sent: Thursday, 31 January 2002 03:43
> > To: [log in to unmask]
> > Subject: advice
> >
> >
> > Hi everyone,
> >
> > What do others think about biochemist(non medical) advising on drug
> > treatment?
> >
> > This comes from the last  ACB case about hyperlipidaemia and advising
> > about
> > statin Rx.
> >
> > Bharat
> >
> >
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