These cutoff limits frequently are used, but where do they come from? I seem
to be unable to find the proper reference
Dr. A. J. Bakker, Klinisch chemicus,
St. Klinisch Chemisch Laboratorium,
Postbus 850,
8901 BR LEEUWARDEN.
Tel.: 058-2888444
Fax: 058-2882227
E-mail: [log in to unmask]
> -----Oorspronkelijk bericht-----
> Van: Jagger Caroline [SMTP:[log in to unmask]]
> Verzonden: woensdag 25 september 2002 10:13
> Aan: [log in to unmask]
> Onderwerp: FW: Microalbuminuria screening
> Urgentie: Hoog
>
>
> From: Myers Martin
> Sent: 24 September 2002 17:00
> To: 'Lance Sandle'; [log in to unmask]
> Subject: RE: Microalbuminuria screening
>
>
>
> Issue 4, April 2002 of the NICE (National Institute for Clinical
> Excellence) Compilation Summary of Guidance, has definitions related to
> microalbumin in the section on: Management of Type 2 Diabete: renal
> disease-prevention and early management
>
> Lower-risk urine albumin excretion: People who have levels of
> microalbuminuria and/or proteinuria lower than those indicated below
>
> Higher-risk urine albumin excretion:
> Microalbuminuria- albumin:creatinine ratio greater than or equal to 2.5
> mg/mmol/L (men) or 3.5 mg/mmol (women), or albumin concentration greater
> than or equal to 20 mg/l
> and/or
> Proteinuria- albumin:creatinine ratio greater than or equal to 30 mg/mmol
> or albumin concentration greater than or equal to 200mg/L
>
>
> It also states that if microalbuminuria or proteinuria is present, repeat
> twice more within 1 month
>
> It discusses the lack of a clear cut-off point for proteinuria.
>
> It is silent on whether a "higher-risk" patients require either timed
> microalbumin excretion or total protein estimation.
>
> In the text it states that albumin excretion (based on definitions above)
> should be used to classify a patient annually as at "lower risk" or
> "higher risk". "Care" of the patient, it states, is based on whether the
> patient is lower risk or higher risk.
>
> If it's NICE it must be true (shouldn't it)
>
> regards
>
> Martin Myers
>
>
>
>
>
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