> Can I start a conversation regarding the 'dwell-time' between chest pain
> and measurement of Troponin T +/or I ?
> I am very concerned that some people are using 6 hrs and others (like me)
> are using 12.
>
> My feeling to start the discussion is that when using Troponins as a MI
> excludogram, 12 hrs should be used, and that this is the most economic
> usage of the assay, but a 6 hr assay may give too many potentially
> litigenous/dangerous false negatives.
>
> Single assay confirmation of MI for those who can afford it may well be OK
> before 12 hrs, depending on the size of infarct. I can see the attraction
> of earlier tests in case Troponin is being used as a thrombolysis
> indicator, which necessitates treatment within 12 hours.
>
> Horrors - the bandolier article looks as if 'they' will want [admission],
> [3hr] and [12hr] to diagnose MI. Has anyone succeded in convincing their
> trust to transfer adequate funding from Medicine/A&E to Laboratory budgets
> ?
> <http://www.jr2.ox.ac.uk/bandolier/band93/b93-5.html>
>
> I don't think the NSF on hearts is explicit enough.
> With best wishes
>
> Richard
>
>
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