Does anyone have a view on the most appropriate value of the SHBG-
testosterone association constant to use for calculation of free
testosterone in clinical samples?. Sodergard et al (J. Steroid Biochem 16
(1982)801) use a value of 0.6 L/nmol but also quote several other values
from earlier literature. Vermeulen et al (J Clin Endo Metab 84(1999)3666)
suggest using 1.0 L/nmol. These values differ by 40% and therefore give
significantly different calculated values for free testosterone.
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