Dear Mohammed I can see no justification for collecting a 24 hour or any
other timed urine sample on an elderly patient. A calculated clearance is
better than that. Cystatin C has not really been introduced into clinical
practice in many centres yet, Lund in Sweden being one of the few. However
we are about to on the back of a research project involving neonates.
A reference GFR procedures such as iohexol would be much more preferable if
an accurate assessment is required. Why not introduce plasma iohexol
clearance?
Dr David Newman
Scientific Director
South West Thames Institute For Renal Research
St Helier Hospital
Wrythe Lane
Carshalton
Surrey
0208 296 3698
-----Original Message-----
From: This list is an open discussion list for the academic community
working in [mailto:[log in to unmask]]On Behalf Of
Mohammad Al-Jubouri
Sent: 08 January 2002 14:51
To: [log in to unmask]
Subject: Creatinine clearance test using 6 hours timed urine collection
Dear Colleagues
A care of the elderly physician asked whether we could
shorten the time of collection for CCT for his elderly
demented clients who wants to start them on
nephrotoxic drugs and also to help with calculation of
the dose. Given that CCT is only a rough estimate of
GFR, would list members make a concession for such a
request? Has plasma cystatin C found its way to
routine clinical use?
Thanks
Mohammad
=====
Dr. M A Al-Jubouri
Consultant Chemical Pathologist
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