Repeated measures analysis of variance, does anyone have a good source for
understanding and utilizing this ?
As always your assistance is appreciated.
--
Preston H. Long
> From: "Beasley , Brent" <[log in to unmask]>
> Reply-To: "Beasley , Brent" <[log in to unmask]>
> Date: Mon, 19 Feb 2001 16:52:16 -0600
> To: [log in to unmask]
> Subject: Cross sectional studies?
>
> RE: Annals of Intern Med Jan 16th, 2001, vol 134(2):88-95.
>
> Hello Colleagues,
> The study is cross-sectional. 59 pts with Ulc Colitis who get surveillance
> colonoscopies. Analysis was done based upon dividing this group into those
> with vs. without use of Ursodiol (41/59). Use of Ursodiol was assessed 1)
> by chart records and 2) by direct patient contact if not found in records.
> Association of interest was Colonic dysplasia assessed by biopsy (26/59).
> Ursodiol was strongly associated with decreased prevalence of colonic
> dyplasia (32% vs. 72%, OR=0.18).
>
> Questions:
> It seems this study could have been done in a case-control format, dividing
> groups on the basis of dysplasia.
> 1. What would have been the BEST methodology?
> 2. Which methodology would be most conservative/least biased?
> 3.Does it matter?
>
> Brent W. Beasley, M.D.
> St. Luke's Hospital, Dept. of Medical Education
> 4401 Wornall Rd
> Kansas City, MO 64111
> (816) 932-3409
> Fax: (816) 932-5179
> Pager: (816) 440-3968
> [log in to unmask]
>
> "When men have come to the edge of a precipice,
> it is the lover of life who has the spirit to leap backwards,
> and only the pessimist who continues to believe in progress."
> --G. K. Chesterton
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