Yes.It is published in one of the last few issues of the
Scand J Clin Lab Med as a review issue on Laboratory
Performance. The clinical significance based on biology
(European) and total error(American) has been given for
various analytes.
Regards
Vivek
On Sun, 25 Feb 2001 15:58:24 +0100 "Breimer, Lars
{PDC2~Welwyn}" <[log in to unmask]> wrote:
> Dear Colleagues
>
> We all (should) know about analytical and biological variation and their coefficients of variation. And we all have a good idea of what is significant for a patient when we see them in clinic.
>
> Please can someone direct me to a simple summary publication / table / website which gives an idiot's guide to how much the value of analyte must have changed to be a clinically signficant change.
>
> Perhaps such a table does not exist? However, I seem to remember seeing such information. Perhaps it is not reliable or even downright faulty.
>
> Much obliged.
>
>
> Yours sincerely
>
>
>
> Lars Breimer
> MA PhD BM BCh MRCPath Dip Pharm Med
> Clinical Science
> Global Drug Development
> Roche Products Limited
> 40 Broadwater Road
> Welwyn Garden City
> Herts
> AL7 3AY
> U K
> Registration Number 100674
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Vivekanandan Sachidanandam
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