It is not infrequent to find false positives for IgM anti-Toxoplasma anti-
CMV an sometimes anti-Rubella in sera from pregnant women. This we have
noticed with different automated immunoassays such Abbott Axsym ,Roche
Cobas Core II and Bio-merieux Vidas, sometimes with conflicting results
for the same sample on different analyzers. Obviously RF has been ruled out
as a source of interference.
My questions are:
Has this been observed by others?
Should a different cutoff be used for pregnant women?
Any idea for the possible cause of interference?
Bst regards an a happy New Year to everybody,
Bruno Forcina
Laboratorio Forcina
Piazza stazione 78 Galatina Italy
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