Graham,
We've been using Polycal (Nutricia Clinical UK - formerly known as
Fortical) - see Colley CM, Larner JR. The use of Fortical in glucose
tolerance tests. Ann Clin Biochem 1990;27:496-498.
Revised WHO recommendations state:
"the subject should drink 75 g of anhydrous glucose or 82.5 g of glucose
monohydrate (or partial hydrolysates of starch of the equivalent
carbohydrate content) in 250-300 ml of water over the course of 5 minutes."
Full text available via Diabetes UK website
http://www.diabetes.org.uk/info/carerec/newdiagnotic.htm
Joe Begley
Poole Hospital UK
----- Original Message -----
From: "Graham Jones" <[log in to unmask]>
To: <[log in to unmask]>
Sent: Tuesday, December 04, 2001 5:05 AM
Subject: Glucose polymer for OGTT
> Dear Colleagues,
>
> I am writing to ask for information and advice on the use of glucose
> polymer for oral glucose tolerance tests. Glucose polymer seems to be a
> series of linked glucose molecules presumably averaging about 5 molecules
> per chain as the product information suggests an osmolality of about 1/5th
> of standard glucose.
>
> Claimed benefits for glucose polymer in OGTT include better tolerance
> (fewer GIT upsets, nausea or vomiting), more reproduceable results and
less
> effect of drawing water into the GIT.
>
> A study in Clin Chem (1992) indicates very similar values at 2 hours to an
> OGTT using disolved glucose.
>
> From memory glucose polymer is not mentioned in any recent guidelines
about
> OGTT's.
>
> My questions are: does anyone use it? if so with what evidence or support?
> and if anyone has considered it and rejected it what is the basis for the
> rejection?
>
> Thank you in advance,
>
> Graham
> Graham Jones
>
> Staff Specialist in Chemical Pathology
> St Vincent's Hospital, Sydney
> Victoria St, Darlinghurst, 2010
> NSW, Australia
> Ph: (02) 8382-2170 Fax (02) 8382-2489
> [log in to unmask]
>
>
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