I should be interested to learn what the pharmacists' evidence is that
suggests that such correction leads to a better outcome.
Trevor Tickner,
Norwich
> -----Original Message-----
> From: g.challand [SMTP:[log in to unmask]]
> Sent: 28 August 2001 10:30
> To: [log in to unmask]
> Subject: Fw: FW: RE: Phenytoin TDM in hypoalbuminaemic patients
>
> Is this another example of 'lies, damned lies, and algorithms'?!
> Gordon
> ----- Original Message -----
> From: Ball, Graham <mailto:[log in to unmask]>
> To: [log in to unmask]
> <mailto:[log in to unmask]>
> Sent: Friday, August 24, 2001 4:59 PM
> Subject: FW: RE: Phenytoin TDM in hypoalbuminaemic patients
>
>
>
> Our pharmacists would like us to calculate "corrected" Phenytoins in
> hypoalbuminaemic patients.
> I have some reservations, particularly if patients are on several other
> drugs.
>
> They use this formula:
>
> To calculate a "corrected" Cpss for patients with low Serum albumin
> Cp adjusted = ______Cp1_______
> 0.9 (P1)/(P)+ 0.1
>
> Cp1 = steady state serum level observed
> P1 = serum albumin concentration observed
> P = "Normal" serum albumin concentration 40mg/L (sic)
>
>
> Graham Ball
>
>
>
>
> ++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
> This e-mail is confidential and may well also be legally privileged. If
> you have received it in error, you are on notice of its status. Please
> notify us immediately by reply e-mail and then delete this message from
> your system. Please do not copy it or use it for any purposes, or disclose
> its contents to any other person: to do so could be a breach of
> confidence. Any views expressed in this message are those of the
> individual sender, except where the sender specifically states them to be
> the views of the Trust.
>
> Thank you for your co-operation.
>
>
>
---------------------------------------------------------------------------
The information contained in this e-mail is confidential and is intended
only for the named recipient(s). If you are not the intended recipient you
must not copy, distribute, or take any action or reliance on it. If you have
received this e-mail in error, please notify the sender. Any unauthorised
disclosure of the information contained in this e-mail is strictly
prohibited.
|