Hi,
Thanks a lot for all your comments on intention to treat analysis.
I am looking at a RCT by Dutta D et als, 1996 (Efficacy of norfloxacin
and doxycycline for the treatment of V cholerae O139 infection)
where 160 patients were enrolled in the study but just 111 analysed.
The difference 49 subjects were not included in the analysis because
they showed culture (-) to Vcholerae O139. There's a table that
shows comparable characteristics of the patients on admission, but
for the 111 not for the 160. Is this the way it should be? OR the
right way would be showing the table with all the subjects entered and
randomized for the study (i.e 160) and as we have analyzed a 69% of
that (i.e. 111) because of 49 not being O139 we can conclude that
realibility of the study is compromised?
Would this be an example of not having followed the intention to treat
analyis, i.e. once randomised always analysed?
Thanks a lot
Julia
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