There are two points which I would like to mention:
1. You may need to re-examine your PTH reference range
and establish your own local values.
2. If the calcium result at the upper part of the
reference range you may regard these as normocalcaemic
hyperparathyroidism. If the calcium at the lower end
of the reference range then secondary
hyperparathyroidism is a possibility.
regards.
--- Bruce Campbell <[log in to unmask]> wrote: > In
recent times we have been seeing requests for PTH
> levels in
> normocalcaemic patients, probably as part of an
> "osteoporosis" or
> "osteoporosis risk" investigation. We have seen a
> number of patients with
> elevated PTH levels (Immulite intact PTH assay) and
> normal serum calcium.
> PTH can be more than twice the upper RR limit.
> Most patients are
> otherwise apparently healthy and the most recent had
> normal 24 hour urinary
> calcium excretion. We checked vitamin D status in
> one patient despite
> normal serum ALP and found 25-OH D to be
> unremarkable.
>
> I would be grateful for any thoughts as to what is
> going on here.
>
> Bruce Campbell
>
> ************************************
> Bruce Campbell FRCPA, FAACB
> Chemical Pathologist
> Sullivan Nicolaides Pathology
> PO Box 344 Indooroopilly Qld 4068 Australia
> ph 61 (0)7 3377 8672
> fax 61 (0)7 3870 5989
> email [log in to unmask]
> *************************************
>
=====
Dr. M A Al-Jubouri
Consultant Chemical Pathologist
Whiston Hospital
Prescot
Merseyside L35 5DR
UK
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