Performing Creatine kinase isoenzymes by
electrophoresis may be helpful in identifying a fluid
as CSF, sinc CKBB band will only be detected. A serum
sample will show mainly CKMM band and a mucus
secretion will show no bands. Contamination of CSF by
blood may result in appearnce of extra CKMM band as
well as the usual CKBB. In such cases a comparison
with serum CK isoenzyme pattern may resolve the issue.
regards.
--- Frederic Cotton <[log in to unmask]> wrote: > We
often receive liquids from patients in
> neurosurgery and are asked to exclude the presence
> of CSF.
> The only CSF-specific analyte we know is
> Beta2-transferrin (tho-fraction).
> Does anyone know a quick method to screen for the
> presence of it in such liquids ?
> Is there another worthfull analyse to make ?
> Thank you in advance,
> Frederic Cotton
> > BEGIN:VCARD
> VERSION:2.1
> N:Cotton;Frederic
> FN:Frederic Cotton
> ORG:Hôpital Erasme - Université Libre de
> Bruxelles;Clinical Chemistry
> TITLE:PharmD - Clinical Pathologist
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>
=====
Dr. M A Al-Jubouri
Consultant Chemical Pathologist
Whiston Hospital
Prescot
Merseyside L35 5DR
UK
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