A classical cause of negative interference with the Jaffe method is high
bilirubin concentration.
Clin Chem 1992;38/9:1749-51
F.Cotton
Erasme Hospital - Brussels
----- Original Message -----
From: J.M. Pekelharing <[log in to unmask]>
To: <[log in to unmask]>
Sent: Saturday, November 25, 2000 11:55 AM
Subject: falsely low creatinine
> We found a falsely lowered creatinine, measured on a Vitros analyser, in
one
> sample in a series of four from an IC-patient:
>
> date: nov 15 nov 17 nov 18 nov 18
> BUN: 19.1 24.5 26.1 28.2 (url 7.0)
> Creat: 172 265 20 !!! 312 (url 130)
>
> All other results fit, so no sample mix-up. Repeating the result of 20 a
few
> hours later in the same sample, we found 70, considerably higher but still
> not fitting. Medication did not give us a clue.
>
> Has someone seen this before and found the cause? Vitros-specific problem?
>
> Thanks.
>
> Maurits Pekelharing
> clinical biochemist
> Reinier de Graaf Hospital Group
> Delft, the Netherlands
> [log in to unmask]
>
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