Dear Helen,
Does tamoxifen cross-react in this assay?
Yours sincerely,
Lars Breimer
Clinical Science
Roche Products Limited
40 Broadwater Road
Welwyn Garden City
AL7 3 AY
Registration Number 100674
tel + UK + 1707 36 59 74
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> -----Original Message-----
> From: Grimes, Helen [SMTP:[log in to unmask]]
> Sent: Friday, March 10, 2000 12:33 PM
> To: [log in to unmask]
> Subject: Suppression of oestradiol by Tamoxifen
>
> A 35 year old female, has had mastectomy in early 1999 and chemotherapy
> for
> breast cancer, and is now on Tamoxifen. On 16/2/00 we reported FSH=7.2,
> LH=7.3 mIU/ml, oestradiol =1633 pmol/l (Wallac Delfia), on 1/3/00 FSH=1.5,
> LH=1.6 mIU/ml, oestradiol =2726 pmol/l. Tamoxifen was expected to suppress
> oestradiol, and do others monitoring such patients find that it does.
> Would
> you suggest an oestrogen secreting tumour or is there anything else we
> should be doing.
>
> Helen Grimes, Dept of Clinical Biochemistry, University College Hospital,
> Galway, Ireland.
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