Dear Dr Williams
I have to admit to complete ignorance of nicotine metabolism. Please
explain to me how the metabolism of nicotine absorbed through the
trans-pulmonary route might differ from the metabolism of nicotine absorbed
through the trans-cutaneous route. Or have I missed the point?
David G Williams wrote:
Cotinine is the major metabolite of nicotine. I think that
it is
unlikely that nicotine patches would contain cotinine,
ergo, the
presence of cotinine in the sample indicates recent
smoking.
David G Williams
Patrick B Deegan
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