A guide to diagnostic clinical chemistry by RN Walmsley and GH white makes
use of random urine specimens in the investigation of hyper and
hyponatraemia. I have always found this book by far the best in its
explanation of these disorders so I would have to say that I think random
urine electrolytes and osmolality are useful. Of course even though most of
the day "On the desk" involves authorising and interpreting U&Es (urea and
electrolytes - prepare to be shot down about this term !) I still spend a
lot of time looking through text books for help on this subject !
Craig Webster
Senior Clinical Biochemist
Nottingham City Hospital
I would appreciate the views of my colleagues (and any others who
read this e-mail) on the use of random urine specimens in
diagnosis and monitoring of electrolyte disturbances. In addition
are there any views on the value of a random urine osmolality in
looking at concentration defects. Are random urines ever
appropriate for these investigations and if so what are the limits of
their usefulness? I was taught that random urine electrolytes,
especially on inpatients, are generally unhelpful especially in those
on iv therapy or diuretics. Is this really true or should I revise my
opinions.
Craig Webster
Senior Clinical Biochemist
Nottingham City Hospital
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