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This is a repeat, but first time round I forgot to
include some crucial information about money!



Applications are invited for a BBSRC CASE PhD studentship
starting in October 1999.  Industrial CASE studentships are   
worth approximately 3,000 pounds more than a standard
research council studentship. 

The student will be based in the Department of Statistical
Science, University College London.

The sponsoring company in PIC, the world's leading pig
breeding organisation.

The research topic is the analysis of high density genotyping
information; in particular how to use the information from
thousands of genetic markers to guide a breeding programme.
Some more details are given below.

For more information contact Dr Tom Fearn at UCL (email:
[log in to unmask], tel: 0171 380 7189).

To apply: send a CV to
 Dr Tom Fearn,
 Department of Statistical Science,
 University College London,
 Gower Street,
 London, WC1E 6BT.

Applications will close on Tuesday 4th May.


Topic: The analysis of High Density Genotyping information. 

In animal breeding, DNA information comes from a small number
of genetic marker tests. Regression analysis is used to study
the link between markers and traits of interest. With new DNA
technology like GeneChip technology, the information per
animal will come from 1000's of markers. This will require
new approaches for data analysis.

In general we deal with a trait of interest and a lot of 
information that is potentially related to that trait. The
objective is to find linear and non-linear links between the
trait and the mass of information.

Other examples are fertility in males and a lot of information
collected on the ejaculates or growth rate of individual
animals and a lot of information collected about the feed, 
climatic conditions and health status.

The objective of the project is to develop general solutions
and to evaluate these with relevant cases as presented by the
sponsor (PIC). The use of high density genotype information in
animal breeding is the topic that will give direction to the
project.

The approaches explored are likely to include ideas from
Bayesian statistics, from chemometrics, and possibly from
artificial intelligence. 



  




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