> I am a biologist, considering whether or not it is correct to carry out a
> Bonferonni procedure on my data, and would be very grateful for any advice.
> (details deleted)
> Thanks, 
> Steve Rossiter

We compared (by simulation) a number of corrections for multiplicity, see

Brown, B. W. and Russell, K. "Methods Correcting for Multiple Testing:
Operating Characteristics."  Statistics in Medicine, 16: 2511-2528 (1997).

Bonferroni is, of course, very conservative.  We like the graphic method
described below as a starting point to seeing what is going on.

Schweder, T. and Spjotvoll, E. "Plots of P-values to evaluate many tests
simultaneously." Biometrika 69: 493-502 (1982)

Code for these methods is available on our web site


                                       Barry W. Brown
                                       Department of Biomathematics, 
                                            Box 237
                                       University of Texas M. D.
                                            Anderson Cancer Center
                                       1515 Holcombe Blvd
                                       Houston, TX 77030

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