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On a related topic I was involved with a drink driving case where the
defense was that ranitidine inhibited gastric ADH, thereby causing
increased alcohol levels.   Of course alcohol is predominantly
metabolised by hepatic ADH as well as by the mixed enzyme oxidative
system in the liver.  So it may be there may be a deficiency in gastric
ADH (eg japanese, females, atrophic gastritis), but as far as I can tell
from the literature, in all cases, alcohol levels are similar from
similar doses. 
-- 
Dr Graham Mould
Guildford Clinical Pharmacology Unit
Royal Surrey County Hospital
Guildford, Surrey, UK
Tel 00 44 1483 (0) 406886
Fax 00 44 1483 (0) 455375


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