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We have a patient with a carcinoma in the head of the pancreas, who now has developed a dysfunction in the drain of the galbladder. I was struck by the creatinine values: date 1/6 3/6 4/6 creat 120 221 425 bili 513 352 287 AF 791 768 593 Amylase 73 192 335 Lipase 75 340 564 We measure creatinine by a kinetic Jaffe method, with automatic correction for bilirubin on an Hitachi 911. Inspection of the reaction curve shows a normal pattern. No clinical details available (e.g. urine production). Has anyone experience with this combination of results? Is it tissue autolysis while the biliary obstruction resolves? Any comment appreciated. Raymond Wulkan Zuiderziekenhuis Rotterdam The Netherlands %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%