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Dear FSL experts,

I like to compare one subject to a group of 20 subjects. Can I use "-1" in randomise (sign-flipping)?

randomise -i GM_mod_merg_s3 -m GM_mask -o fslvbm -d design.mat -t design.con -1 -T -n 5000

Should I add variance smoothing (-v) in addition to smoothing ? How to estimate the appropriate value of -v? 

fslmaths GM_mod_merg -s 3 GM_mod_merg_s3
randomise -i GM_mod_merg_s3 -m GM_mask -o fslvbm -d design.mat -t design.con -1 -v 1 -T -n 5000


Thank you

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