I have a question regarding a 2x2 model (gender x diagnostic group) I am running in SPM. There are 4 groups. The male groups have 2x as many participants as the female groups (i.e., 140 versus 70). Is there a way to account for this difference in SPM, perhaps by weighing the contrasts???
Thanks in advance,
Rachel A. Rabin, PhD
Icahn School of Medicine at Mount Sinai
Friedman Brain Institute
Department of Psychiatry
Neuropsychoimaging of Addiction and Related Conditions (NARC)
1470 Madison Avenue, 10th Floor 120