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Not really antenatal - but may be worth looking at the findings from the ‘ANODE’ trial, not sure if results/findings yet published...

https://www.npeu.ox.ac.uk/anode

Tara Pauley
Associate Director -
Pathway to Excellence Lead®
Northampton General Hospital NHS




On 9 Aug 2018, at 23:40, Celia Grigg <[log in to unmask]<mailto:[log in to unmask]>> wrote:


Hi Sheena,

I'm not sure that there's much on antenatal ABs, the focus has been on intrapartal ones.
Here's a few with an antenatal focus:

Nogacka AM et al (2018) Early microbiota, antibiotics and health. Cellular Molecular Life Sciences 75:83-91,  https://doi.org/10.1007/s00018-017-2670-2.

Gonzalez-Perez G et al (2016) Maternal antibiotic treatment impacts development of the neonatal intestinal microbiome and antiviral immunity. Journal of Immunology 196:3768-3779. doi: 10.4049/jimmunol.1502322.

Levin AM et al (2016) Joint effects of pregnancy, sociocultural and environmental factors on early life gut microbiome structure and diversity. Scientific Reports, 6:31775. DOI: 10.1038/srep31775.


It's such an interesting field!! (I'm just starting a research project in the area.) There's still debate about whether the initial colonisation begins in-utero or not, eg:

Chong C et al (2018) Factors affecting gastrointestinal microbiome development in neonates. Nutrients 10, 274. doi:10.3390/nu10030274

Perez-Muñoz et al. (2017) A critical assessment of the "sterile womb" and "in utero colonization" hypotheses: implications for research on the pioneer infant microbiome. Microbiome 5:48. DOI 10.1186/s40168-017-0268-4.

Best wishes

Celia.


On 10 August 2018 at 01:33 SHEENA BYROM <[log in to unmask]<mailto:[log in to unmask]>> wrote:

Dear friends,

Can anyone point me to research papers or articles on the impact of antibiotics taken in the antenatal period please?
With very best wishes,

Sheena

Website: sheenabyrom.com<http://www.sheenabyrom.com>

Twitter: @SagefemmeSB<https://twitter.com/SagefemmeSB>




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